PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NCOA5	CTRPv2	pan-cancer	AAC	-0.15	7e-05
mRNA	JRK	CCLE	pan-cancer	AAC	0.2	7e-05
mRNA	ANKDD1A	CTRPv2	pan-cancer	AAC	-0.14	7e-05
mRNA	KTI12	CTRPv2	pan-cancer	AAC	-0.16	7e-05
mRNA	TRMU	CTRPv2	pan-cancer	AAC	-0.15	7e-05
mRNA	HBZ	CTRPv2	pan-cancer	AAC	0.14	7e-05
mRNA	TMPRSS12	CTRPv2	pan-cancer	AAC	0.14	7e-05
mRNA	YDJC	CTRPv2	pan-cancer	AAC	0.15	7e-05
mRNA	NTN4	CTRPv2	pan-cancer	AAC	0.15	7e-05
mRNA	CDH1	CCLE	pan-cancer	AAC	0.23	7e-05