PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	BAIAP2	CTRPv2	pan-cancer	AAC	0.17	5e-05
mRNA	ABCF2	CTRPv2	pan-cancer	AAC	-0.15	5e-05
mRNA	DCPS	CTRPv2	pan-cancer	AAC	-0.16	5e-05
mRNA	CDT1	CTRPv2	pan-cancer	AAC	0.18	5e-05
mRNA	MBTPS2	CCLE	pan-cancer	AAC	-0.2	5e-05
mRNA	HNF1B	CCLE	pan-cancer	AAC	0.22	5e-05
mRNA	PTAFR	CTRPv2	pan-cancer	AAC	0.16	5e-05
mRNA	BMI1	CTRPv2	pan-cancer	AAC	-0.15	5e-05
mRNA	ZNF407	CTRPv2	pan-cancer	AAC	-0.16	5e-05
mRNA	ILKAP	CTRPv2	pan-cancer	AAC	-0.15	5e-05