PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GPRIN1	CTRPv2	pan-cancer	AAC	-0.18	6e-06
mRNA	SF3B2	CTRPv2	pan-cancer	AAC	-0.16	6e-06
mRNA	YPEL4	CTRPv2	pan-cancer	AAC	0.16	6e-06
mRNA	TRIM28	CCLE	pan-cancer	AAC	0.2	6e-06
mRNA	LAD1	CTRPv2	pan-cancer	AAC	0.2	6e-06
mRNA	TNKS1BP1	CTRPv2	pan-cancer	AAC	0.2	6e-06
mRNA	GDF2	CTRPv2	pan-cancer	AAC	0.16	7e-06
mRNA	LASP1	CCLE	pan-cancer	AAC	0.22	7e-06
mRNA	GNG4	CTRPv2	pan-cancer	AAC	-0.17	7e-06
mRNA	C1orf189	CTRPv2	pan-cancer	AAC	-0.16	7e-06