PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RP4-635E18.9	CTRPv2	pan-cancer	AAC	-0.17	5e-06
mRNA	APOL4	CCLE	pan-cancer	AAC	0.22	5e-06
mRNA	KLF5	CCLE	pan-cancer	AAC	0.29	5e-06
mRNA	STK38	CCLE	pan-cancer	AAC	0.22	5e-06
mRNA	EEF1A1	CTRPv2	pan-cancer	AAC	0.18	5e-06
mRNA	PML	CTRPv2	pan-cancer	AAC	0.18	5e-06
mRNA	LAMTOR2	CTRPv2	pan-cancer	AAC	-0.17	5e-06
mRNA	PKLR	CTRPv2	pan-cancer	AAC	0.16	6e-06
mRNA	UAP1L1	CTRPv2	pan-cancer	AAC	-0.18	6e-06
mRNA	MTX1	CTRPv2	pan-cancer	AAC	-0.17	6e-06