PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FOXB1	CTRPv2	pan-cancer	AAC	0.17	3e-06
mRNA	BTC	CTRPv2	pan-cancer	AAC	0.18	3e-06
mRNA	STXBP5L	CTRPv2	pan-cancer	AAC	-0.17	3e-06
mRNA	NFE2	CTRPv2	pan-cancer	AAC	0.17	4e-06
mRNA	TMEM63C	CTRPv2	pan-cancer	AAC	-0.17	4e-06
mRNA	PABPC3	CTRPv2	pan-cancer	AAC	0.17	4e-06
mRNA	KBTBD4	CTRPv2	pan-cancer	AAC	-0.17	4e-06
mRNA	JUP	CCLE	pan-cancer	AAC	0.26	4e-06
mRNA	ZNF775	CTRPv2	pan-cancer	AAC	-0.18	5e-06
mRNA	IPO9	CTRPv2	pan-cancer	AAC	-0.18	5e-06