PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	OSBPL6	CTRPv2	pan-cancer	AAC	-0.15	4e-05
mRNA	ZNF416	CCLE	pan-cancer	AAC	0.19	4e-05
mRNA	HEPH	CTRPv2	pan-cancer	AAC	0.16	4e-05
mRNA	ID1	CCLE	pan-cancer	AAC	0.27	4e-05
mRNA	C1orf116	CCLE	pan-cancer	AAC	0.24	4e-05
mRNA	RNF20	CTRPv2	pan-cancer	AAC	-0.16	4e-05
mRNA	GDAP1	CTRPv2	pan-cancer	AAC	-0.15	4e-05
mRNA	BBS12	CTRPv2	pan-cancer	AAC	0.15	4e-05
mRNA	COPRS	CTRPv2	pan-cancer	AAC	-0.16	5e-05
mRNA	HSH2D	CTRPv2	pan-cancer	AAC	0.17	5e-05