PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	LNP1	CTRPv2	pan-cancer	AAC	-0.17	8e-06
mRNA	NT5C2	CTRPv2	pan-cancer	AAC	0.17	8e-06
mRNA	GRIPAP1	CTRPv2	pan-cancer	AAC	-0.17	8e-06
mRNA	FSD1	CTRPv2	pan-cancer	AAC	-0.19	8e-06
mRNA	ZNF256	CCLE	pan-cancer	AAC	0.21	8e-06
mRNA	BTC	CCLE	pan-cancer	AAC	0.23	8e-06
mRNA	TET3	CCLE	pan-cancer	AAC	0.23	8e-06
mRNA	RPS6KA1	CCLE	pan-cancer	AAC	0.24	9e-06
mRNA	ACHE	CTRPv2	pan-cancer	AAC	0.16	9e-06
mRNA	CCDC142	CTRPv2	pan-cancer	AAC	-0.16	9e-06