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TAE684

Synonyms

SourcesNames Used
CCLE, GDSC1000TAE684
CTRPv2NVP-TAE684
PharmacoGx TAE684

External IDs

DatabaseIdentifier
Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Inchikey: QQWUGDVOUVUTOY-UHFFFAOYSA-N
Pubchem: 16038120

FDA Approval Status

Not Approved
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Top molecular features associated with response to TAE684


Feature TypeStandardized
Nominal ANOVA
mRNA GPRIN3 CTRPv2 pan-cancer AAC 0.24 3e-12
mRNA JAK3 CTRPv2 pan-cancer AAC 0.28 3e-12
mRNA UPK1B GDSC1000 pan-cancer AAC 0.36 4e-12
mRNA SERPINB4 GDSC1000 pan-cancer AAC 0.34 4e-12
mRNA TMPRSS11D CTRPv2 pan-cancer AAC 0.23 6e-12
mRNA IL1R2 CTRPv2 pan-cancer AAC 0.23 6e-12
mRNA MAP4K2 CTRPv2 pan-cancer AAC -0.26 7e-12
mRNA TMEM260 GDSC1000 pan-cancer AAC 0.35 1e-11
mRNA PRF1 GDSC1000 pan-cancer AAC 0.35 2e-11
mRNA DMBX1 GDSC1000 pan-cancer AAC 0.33 2e-11
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