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TAE684

TAE684

Synonyms

Sources	Names Used
CCLE, GDSC1000	TAE684
CTRPv2	NVP-TAE684
PharmacoGx	TAE684

External IDs

Database	Identifier
Smiles:	CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Inchikey:	QQWUGDVOUVUTOY-UHFFFAOYSA-N
Pubchem:	16038120

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TAE684

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	IL1RAP	GDSC1000	pan-cancer	AAC	0.35	3e-09
mRNA	SLC26A4	GDSC1000	pan-cancer	AAC	0.35	7e-13
mRNA	CTSB	GDSC1000	pan-cancer	AAC	0.36	7e-09
mRNA	ERRFI1	GDSC1000	pan-cancer	AAC	0.36	1e-05
mRNA	HTRA3	GDSC1000	pan-cancer	AAC	0.36	5e-13
mRNA	UPK1B	GDSC1000	pan-cancer	AAC	0.36	4e-12
mRNA	CHSY1	GDSC1000	pan-cancer	AAC	0.37	9e-13
mRNA	TEAD3	GDSC1000	pan-cancer	AAC	0.37	1e-09
mRNA	HAVCR2	GDSC1000	pan-cancer	AAC	0.38	5e-13
mRNA	SOCS3	GDSC1000	pan-cancer	AAC	0.39	3e-15

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