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TAE684

TAE684

Synonyms

Sources	Names Used
CCLE, GDSC1000	TAE684
CTRPv2	NVP-TAE684
PharmacoGx	TAE684

External IDs

Database	Identifier
Smiles:	CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Inchikey:	QQWUGDVOUVUTOY-UHFFFAOYSA-N
Pubchem:	16038120

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TAE684

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RORC	GDSC1000	pan-cancer	AAC	0.34	1e-10
mRNA	SERPINB4	GDSC1000	pan-cancer	AAC	0.34	4e-12
mRNA	IL2RA	GDSC1000	pan-cancer	AAC	0.34	5e-11
mRNA	CD163	GDSC1000	pan-cancer	AAC	0.34	3e-12
mRNA	RAB11FIP5	GDSC1000	pan-cancer	AAC	0.34	3e-07
mRNA	GAS1	GDSC1000	pan-cancer	AAC	0.34	5e-08
mRNA	IL1R1	GDSC1000	pan-cancer	AAC	0.34	1e-10
mRNA	TEX29	GDSC1000	pan-cancer	AAC	0.35	2e-11
mRNA	TMEM260	GDSC1000	pan-cancer	AAC	0.35	1e-11
mRNA	PRF1	GDSC1000	pan-cancer	AAC	0.35	2e-11

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