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TAE684

TAE684

Synonyms

Sources	Names Used
CCLE, GDSC1000	TAE684
CTRPv2	NVP-TAE684
PharmacoGx	TAE684

External IDs

Database	Identifier
Smiles:	CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Inchikey:	QQWUGDVOUVUTOY-UHFFFAOYSA-N
Pubchem:	16038120

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TAE684

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TMEM45A	GDSC1000	pan-cancer	AAC	0.2	0.001
mRNA	BTN3A2	GDSC1000	pan-cancer	AAC	0.19	0.001
mRNA	LRRIQ3	CCLE	pan-cancer	AAC	-0.15	0.001
mRNA	RPS6KA3	GDSC1000	pan-cancer	AAC	0.18	0.001
mRNA	ABCC9	CTRPv2	pan-cancer	AAC	0.11	0.001
mRNA	SUPT7L	GDSC1000	pan-cancer	AAC	0.17	0.001
mRNA	LBH	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	ZNF563	GDSC1000	pan-cancer	AAC	-0.17	0.001
mRNA	DIXDC1	GDSC1000	pan-cancer	AAC	0.21	0.001
mRNA	KCTD12	GDSC1000	pan-cancer	AAC	0.18	0.001

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