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TAE684

TAE684

Synonyms

Sources	Names Used
CCLE, GDSC1000	TAE684
CTRPv2	NVP-TAE684
PharmacoGx	TAE684

External IDs

Database	Identifier
Smiles:	CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Inchikey:	QQWUGDVOUVUTOY-UHFFFAOYSA-N
Pubchem:	16038120

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TAE684

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HIST1H2AC	GDSC1000	pan-cancer	AAC	0.18	0.0009
mRNA	INTS12	GDSC1000	pan-cancer	AAC	-0.19	0.0009
mRNA	PYHIN1	CCLE	pan-cancer	AAC	-0.16	0.0009
mRNA	ABCC6	CCLE	pan-cancer	AAC	0.16	0.0009
mRNA	VGLL3	GDSC1000	pan-cancer	AAC	0.18	0.0009
mRNA	BZW2	GDSC1000	pan-cancer	AAC	0.17	0.0009
mRNA	MED19	GDSC1000	pan-cancer	AAC	-0.18	0.0009
mRNA	MYO1F	CCLE	pan-cancer	AAC	0.16	0.0009
mRNA	LAMC3	CTRPv2	pan-cancer	AAC	-0.12	0.0009
mRNA	GSX1	CCLE	pan-cancer	AAC	-0.15	0.0009

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