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TAE684

TAE684

Synonyms

Sources	Names Used
CCLE, GDSC1000	TAE684
CTRPv2	NVP-TAE684
PharmacoGx	TAE684

External IDs

Database	Identifier
Smiles:	CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Inchikey:	QQWUGDVOUVUTOY-UHFFFAOYSA-N
Pubchem:	16038120

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TAE684

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	EPB41	GDSC1000	pan-cancer	AAC	-0.2	0.001
mRNA	ABHD6	GDSC1000	pan-cancer	AAC	-0.21	0.001
mRNA	IFNGR1	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	POLR3K	GDSC1000	pan-cancer	AAC	-0.19	0.001
mRNA	COPS7A	CTRPv2	pan-cancer	AAC	-0.12	0.001
mRNA	GLO1	CTRPv2	pan-cancer	AAC	-0.11	0.001
mRNA	GUCA2A	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	ZNF570	CTRPv2	pan-cancer	AAC	-0.12	0.001
mRNA	PRSS27	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	IGF2	CTRPv2	pan-cancer	AAC	0.12	0.001

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