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TAE684

TAE684

Synonyms

Sources	Names Used
CCLE, GDSC1000	TAE684
CTRPv2	NVP-TAE684
PharmacoGx	TAE684

External IDs

Database	Identifier
Smiles:	CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
Inchikey:	QQWUGDVOUVUTOY-UHFFFAOYSA-N
Pubchem:	16038120

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TAE684

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	C9orf84	CTRPv2	pan-cancer	AAC	0.19	3e-08
mRNA	AMER2	CCLE	pan-cancer	AAC	0.25	3e-08
mRNA	NCR1	GDSC1000	pan-cancer	AAC	0.28	3e-08
mRNA	DISC1	CTRPv2	pan-cancer	AAC	0.19	4e-08
mRNA	KIRREL2	CTRPv2	pan-cancer	AAC	0.19	4e-08
mRNA	SLC9A7	CTRPv2	pan-cancer	AAC	-0.19	4e-08
mRNA	RYR2	CTRPv2	pan-cancer	AAC	0.19	4e-08
mRNA	AICDA	CCLE	pan-cancer	AAC	-0.26	4e-08
mRNA	CD22	CTRPv2	pan-cancer	AAC	-0.2	4e-08
mRNA	FNDC3B	CCLE	pan-cancer	AAC	0.26	4e-08

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