1. Home/
  2. Compounds/
  3. Imatinib

Imatinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMImatinib
CTRPv2imatinib
PharmacoGx Imatinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: KTUFNOKKBVMGRW-UHFFFAOYSA-N
Pubchem: 5291

Annotated Targets

KIT, ABL1, CSF1R, DDR1, NTRK1, PDGFRA, PDGFRB, RET, BCR

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to Imatinib


Feature TypeStandardized
Nominal ANOVA
mRNA GAB2 GDSC1000 pan-cancer AAC 0.41 1e-14
mRNA HMBS CTRPv2 pan-cancer AAC 0.27 2e-14
mRNA CISH GDSC1000 pan-cancer AAC 0.41 4e-14
mRNA C7orf34 CTRPv2 pan-cancer AAC 0.27 4e-14
mRNA STAT5A CTRPv2 pan-cancer AAC 0.3 5e-14
mRNA TAL1 CTRPv2 pan-cancer AAC 0.27 6e-14
mRNA GFI1B CTRPv2 pan-cancer AAC 0.26 7e-14
mRNA GRAP2 CTRPv2 pan-cancer AAC 0.27 9e-14
mRNA SPTA1 CTRPv2 pan-cancer AAC 0.26 1e-13
mRNA PRKCB CTRPv2 pan-cancer AAC 0.31 2e-13
Download CSV