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Imatinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMImatinib
CTRPv2imatinib
PharmacoGx Imatinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: KTUFNOKKBVMGRW-UHFFFAOYSA-N
Pubchem: 5291

Annotated Targets

KIT, ABL1, CSF1R, DDR1, NTRK1, PDGFRA, PDGFRB, RET, BCR

FDA Approval Status

Approved
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Top molecular features associated with response to Imatinib


Feature TypeStandardized
Nominal ANOVA
mRNA TRMT1 FIMM pan-cancer AAC 0.46 0.005
mRNA BAG2 CTRPv2 pan-cancer AAC 0.1 0.005
mRNA TMEM243 CTRPv2 pan-cancer AAC -0.1 0.005
mRNA RPL18 CTRPv2 pan-cancer AAC 0.11 0.005
mRNA HIST1H3E CTRPv2 pan-cancer AAC 0.1 0.005
mRNA RGS1 GDSC1000 pan-cancer AAC -0.15 0.005
mRNA SERTAD2 GDSC1000 pan-cancer AAC -0.15 0.005
mRNA ODF3B CTRPv2 pan-cancer AAC -0.1 0.005
mRNA AIM2 GDSC1000 pan-cancer AAC -0.16 0.005
mRNA PDCD2 GDSC1000 pan-cancer AAC 0.16 0.005
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