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Imatinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMImatinib
CTRPv2imatinib
PharmacoGx Imatinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: KTUFNOKKBVMGRW-UHFFFAOYSA-N
Pubchem: 5291

Annotated Targets

KIT, ABL1, CSF1R, DDR1, NTRK1, PDGFRA, PDGFRB, RET, BCR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Imatinib


Feature TypeStandardized
Nominal ANOVA
mRNA MLLT10 CTRPv2 pan-cancer AAC 0.22 1e-08
mRNA OR51V1 CTRPv2 pan-cancer AAC 0.2 1e-08
mRNA HSH2D CTRPv2 pan-cancer AAC 0.23 1e-08
mRNA MB21D1 CTRPv2 pan-cancer AAC 0.21 2e-08
mRNA CDT1 CTRPv2 pan-cancer AAC 0.24 2e-08
mRNA NCOA4 CTRPv2 pan-cancer AAC 0.2 2e-08
mRNA EIF3E CTRPv2 pan-cancer AAC 0.21 2e-08
mRNA KLF1 GDSC1000 pan-cancer AAC 0.28 2e-08
mRNA LEPR GDSC1000 pan-cancer AAC 0.29 2e-08
mRNA ZHX1 CTRPv2 pan-cancer AAC 0.2 2e-08
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