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Imatinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMImatinib
CTRPv2imatinib
PharmacoGx Imatinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: KTUFNOKKBVMGRW-UHFFFAOYSA-N
Pubchem: 5291

Annotated Targets

KIT, ABL1, CSF1R, DDR1, NTRK1, PDGFRA, PDGFRB, RET, BCR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Imatinib


Feature TypeStandardized
Nominal ANOVA
mRNA SLC2A4 CTRPv2 pan-cancer AAC 0.21 7e-09
mRNA HMBOX1 CTRPv2 pan-cancer AAC 0.27 7e-09
mRNA DLK1 FIMM pan-cancer AAC 0.91 7e-09
mRNA RPL7A CTRPv2 pan-cancer AAC 0.22 8e-09
mRNA ZNF175 GDSC1000 pan-cancer AAC 0.3 8e-09
mRNA P2RY1 CTRPv2 pan-cancer AAC 0.21 8e-09
mRNA MYO16 CTRPv2 pan-cancer AAC 0.2 9e-09
mRNA GNA15 CTRPv2 pan-cancer AAC 0.22 1e-08
mRNA NUP43 CTRPv2 pan-cancer AAC 0.21 1e-08
mRNA PDCD2 CTRPv2 pan-cancer AAC 0.21 1e-08
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