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Imatinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMImatinib
CTRPv2imatinib
PharmacoGx Imatinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: KTUFNOKKBVMGRW-UHFFFAOYSA-N
Pubchem: 5291

Annotated Targets

KIT, ABL1, CSF1R, DDR1, NTRK1, PDGFRA, PDGFRB, RET, BCR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Imatinib


Feature TypeStandardized
Nominal ANOVA
mRNA PAQR9 CTRPv2 pan-cancer AAC 0.21 3e-09
mRNA ENPP3 CTRPv2 pan-cancer AAC 0.21 3e-09
mRNA ARG1 CTRPv2 pan-cancer AAC 0.21 3e-09
mRNA OSM GDSC1000 pan-cancer AAC 0.33 4e-09
mRNA CD34 FIMM pan-cancer AAC 0.85 4e-09
mRNA ATP6V0A2 CTRPv2 pan-cancer AAC 0.23 4e-09
mRNA SPN CTRPv2 pan-cancer AAC 0.29 4e-09
mRNA SLC30A10 CTRPv2 pan-cancer AAC 0.21 5e-09
mRNA TUBB1 CTRPv2 pan-cancer AAC 0.2 5e-09
mRNA EGFL7 CTRPv2 pan-cancer AAC 0.2 6e-09
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