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Imatinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMImatinib
CTRPv2imatinib
PharmacoGx Imatinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: KTUFNOKKBVMGRW-UHFFFAOYSA-N
Pubchem: 5291

Annotated Targets

KIT, ABL1, CSF1R, DDR1, NTRK1, PDGFRA, PDGFRB, RET, BCR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Imatinib


Feature TypeStandardized
Nominal ANOVA
mRNA HLA-F CTRPv2 pan-cancer AAC -0.1 0.005
mRNA EFCC1 FIMM pan-cancer AAC 0.49 0.005
mRNA CKB FIMM pan-cancer AAC 0.48 0.005
mRNA GLCCI1 GDSC1000 pan-cancer AAC -0.17 0.005
mRNA TRIM10 CTRPv2 pan-cancer AAC 0.099 0.005
mRNA FERMT3 GDSC1000 pan-cancer AAC 0.27 0.005
mRNA GMFG GDSC1000 pan-cancer AAC 0.33 0.005
mRNA GRIPAP1 CTRPv2 pan-cancer AAC -0.11 0.005
mRNA FOXK2 GDSC1000 pan-cancer AAC 0.16 0.005
mRNA RPL10A CTRPv2 pan-cancer AAC 0.12 0.005
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