1. Home/
  2. Compounds/
  3. Imatinib

Imatinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMImatinib
CTRPv2imatinib
PharmacoGx Imatinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: KTUFNOKKBVMGRW-UHFFFAOYSA-N
Pubchem: 5291

Annotated Targets

KIT, ABL1, CSF1R, DDR1, NTRK1, PDGFRA, PDGFRB, RET, BCR

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to Imatinib


Feature TypeStandardized
Nominal ANOVA
mRNA ADCK5 GDSC1000 pan-cancer AAC 0.15 0.005
mRNA LRFN4 GDSC1000 pan-cancer AAC 0.15 0.005
mRNA PATL2 GDSC1000 pan-cancer AAC -0.18 0.005
mRNA SPIN3 GDSC1000 pan-cancer AAC -0.15 0.005
mRNA SIGLEC7 CTRPv2 pan-cancer AAC -0.1 0.005
mRNA UBE2H GDSC1000 pan-cancer AAC -0.16 0.005
mRNA DBI CTRPv2 pan-cancer AAC -0.1 0.005
mRNA IZUMO4 GDSC1000 pan-cancer AAC -0.16 0.005
mRNA BCL2L13 CTRPv2 pan-cancer AAC 0.11 0.005
mRNA WIPF1 GDSC1000 pan-cancer AAC -0.26 0.005
Download CSV