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Imatinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMImatinib
CTRPv2imatinib
PharmacoGx Imatinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: KTUFNOKKBVMGRW-UHFFFAOYSA-N
Pubchem: 5291

Annotated Targets

KIT, ABL1, CSF1R, DDR1, NTRK1, PDGFRA, PDGFRB, RET, BCR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Imatinib


Feature TypeStandardized
Nominal ANOVA
mRNA ARNT FIMM pan-cancer AAC -0.53 0.005
mRNA SEC61B GDSC1000 pan-cancer AAC -0.14 0.005
mRNA TKTL2 CTRPv2 pan-cancer AAC 0.1 0.005
mRNA TLR10 GDSC1000 pan-cancer AAC -0.16 0.005
mRNA ELP3 GDSC1000 pan-cancer AAC 0.17 0.005
mRNA ZIK1 GDSC1000 pan-cancer AAC 0.15 0.005
mRNA ZNF234 GDSC1000 pan-cancer AAC 0.15 0.005
mRNA TSTA3 CTRPv2 pan-cancer AAC 0.11 0.005
mRNA CXCL12 CTRPv2 pan-cancer AAC 0.1 0.005
mRNA MRPS34 FIMM pan-cancer AAC -0.47 0.005
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