About
Documentation
Cite Us!
Github
Download
News
Explore
Batch Query
Search
Site
Home
About
Documentation
PharmacoGx
Cite Us!
Tools
Explore
Batch Query
Search
GitHub
Datatypes
datasets
cell lines
tissues
drugs
genes
experiments
Home
/
Compounds
/
BMS-754807
BMS-754807
Synonyms
Sources
Names Used
GDSC1000
,
FIMM
,
CTRPv2
BMS-754807
PharmacoGx
BMS-754807
External IDs
Database
Identifier
Smiles:
CC1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F
Inchikey:
LQVXSNNAFNGRAH-QHCPKHFHSA-N
Pubchem:
24785538
Annotated Targets
INSR
,
IGF1R
,
AKT1
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with
BMS-754807 (per dataset)
0
100
200
300
400
500
600
700
800
900
# cell lines
CCLE
gCSI
GRAY
UHNBreast
FIMM
CTRPv2
GDSC1000
0
0
0
0
50
840
932
Download SVG
Number of tissues tested with BMS-754807
(per dataset)
0
5
10
15
20
25
30
35
# tissues
CCLE
gCSI
GRAY
UHNBreast
FIMM
CTRPv2
GDSC1000
0
0
0
0
4
25
35
Download SVG
Dataset Select
all
GDSC1000
FIMM
CTRPv2
BMS-754807: AAC
AAC
0.00
0.10
0.20
0.30
0.40
0.50
0.60
0.70
EW-1
EW-1
KMS-26
KMS-26
NB(TU)1-10
NB(TU)1-10
ES5
ES5
ES1
ES1
A4-Fuk
A4-Fuk
KS-1
KS-1
LB771-HNC
LB771-HNC
NCI-H929
NCI-H929
EW-16
EW-16
RH-41
RH-41
HMV-II
HMV-II
NBsusSR
NBsusSR
NOS-1
NOS-1
MM1-S
MM1-S
201T
201T
MFH-ino
MFH-ino
KMS-34
KMS-34
VCaP
VCaP
COLO-205
COLO-205
KHM-1B
KHM-1B
EW-7
EW-7
ES8
ES8
EW-18
EW-18
KYSE-50
KYSE-50
ML-2
ML-2
SK-N-SH
SK-N-SH
ES4
ES4
RERF-GC-1B
RERF-GC-1B
KMS-11
KMS-11
ES-2
ES-2
TGBC11TKB
TGBC11TKB
U-CH1
U-CH1
WSU-DLCL2
WSU-DLCL2
GSU
GSU
NCI-H1385
NCI-H1385
Raji
Raji
RL
RL
D-502MG
D-502MG
HEC-265
HEC-265
H2591
H2591
DG-75
DG-75
LU-139
LU-139
JAR
JAR
RC-K8
RC-K8
EVSA-T
EVSA-T
DSH1
DSH1
NCI-H720
NCI-H720
SCC-3
SCC-3
EW-24
EW-24
EB-3
EB-3
RPMI-8866
RPMI-8866
KY821
KY821
L-1236
L-1236
UACC-812
UACC-812
SW780
SW780
MHH-PREB-1
MHH-PREB-1
UACC-893
UACC-893
Sarc9371
Sarc9371
SCH
SCH
EW-1
KMS-26
NB(TU)1-10
ES5
ES1
A4-Fuk
KS-1
LB771-HNC
NCI-H929
EW-16
RH-41
HMV-II
NBsusSR
NOS-1
MM1-S
201T
MFH-ino
KMS-34
VCaP
COLO-205
KHM-1B
EW-7
ES8
EW-18
KYSE-50
ML-2
SK-N-SH
ES4
RERF-GC-1B
KMS-11
ES-2
TGBC11TKB
U-CH1
WSU-DLCL2
GSU
NCI-H1385
Raji
RL
D-502MG
HEC-265
H2591
DG-75
LU-139
JAR
RC-K8
EVSA-T
DSH1
NCI-H720
SCC-3
EW-24
EB-3
RPMI-8866
KY821
L-1236
UACC-812
SW780
MHH-PREB-1
UACC-893
Sarc9371
SCH
EW-1: 0.76
Synonyms: EW-1
KMS-26: 0.76
Synonyms: KMS-26, KMS26
NB(TU)1-10: 0.75
Synonyms: NB(TU)1-10
ES5: 0.75
Synonyms: ES5
ES1: 0.74
Synonyms: ES1
A4-Fuk: 0.74
Synonyms: A4-Fuk, A4/Fuk, A4_Fuk, A4FUK
KS-1: 0.73
Synonyms: KS-1
LB771-HNC: 0.72
Synonyms: LB771-HNC
NCI-H929: 0.71
Synonyms: NCI-H929, NCIH929
EW-16: 0.70
Synonyms: EW-16
RH-41: 0.69
Synonyms: RH-41, RH41
HMV-II: 0.68
Synonyms: HMV-II, HMVII
NBsusSR: 0.67
Synonyms: NBsusSR
NOS-1: 0.66
Synonyms: NOS-1
MM1-S: 0.65
Synonyms: MM1-S, MM1S, MM.1S
201T: 0.63
Synonyms: 201T
MFH-ino: 0.62
Synonyms: MFH-ino
KMS-34: 0.62
Synonyms: KMS-34, KMS34
VCaP: 0.61
Synonyms: VCaP, VCAP
COLO-205: 0.61
Synonyms: COLO-205, COLO 205, COLO205
KHM-1B: 0.61
Synonyms: KHM-1B, KHM1B
EW-7: 0.61
Synonyms: EW-7
ES8: 0.60
Synonyms: ES8
EW-18: 0.60
Synonyms: EW-18
KYSE-50: 0.59
Synonyms: KYSE-50
ML-2: 0.59
Synonyms: ML-2, ML2
SK-N-SH: 0.59
Synonyms: SK-N-SH, SKNSH
ES4: 0.59
Synonyms: ES4
RERF-GC-1B: 0.58
Synonyms: RERF-GC-1B
KMS-11: 0.58
Synonyms: KMS-11, KMS11
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
ES-2: 0.02
Synonyms: ES-2, ES2
TGBC11TKB: 0.02
Synonyms: TGBC11TKB
U-CH1: 0.02
Synonyms: U-CH1
WSU-DLCL2: 0.02
Synonyms: WSU-DLCL2, WSUDLCL2
GSU: 0.02
Synonyms: GSU
NCI-H1385: 0.02
Synonyms: NCI-H1385, NCIH1385
Raji: 0.02
Synonyms: Raji, RAJI
RL: 0.02
Synonyms: RL
D-502MG: 0.01
Synonyms: D-502MG
HEC-265: 0.01
Synonyms: HEC-265, HEC265
H2591: 0.01
Synonyms: H2591
DG-75: 0.01
Synonyms: DG-75
LU-139: 0.01
Synonyms: LU-139
JAR: 0.01
Synonyms: JAR
RC-K8: 0.01
Synonyms: RC-K8
EVSA-T: 0.01
Synonyms: EVSA-T, EVSAT, evsat
DSH1: 0.01
Synonyms: DSH1
NCI-H720: 0.01
Synonyms: NCI-H720
SCC-3: 0.00
Synonyms: SCC-3
EW-24: 0.00
Synonyms: EW-24
EB-3: 0.00
Synonyms: EB-3
RPMI-8866: 0.00
Synonyms: RPMI-8866
KY821: 0.00
Synonyms: KY821
L-1236: 0.00
Synonyms: L-1236, L1236
UACC-812: 0.00
Synonyms: UACC-812, UACC812, uacc812
SW780: 0.00
Synonyms: SW780, SW 780, SW_780
MHH-PREB-1: 0.00
Synonyms: MHH-PREB-1
UACC-893: 0.00
Synonyms: UACC-893, UACC893, uacc893
Sarc9371: 0.00
Synonyms: Sarc9371
SCH: 0.00
Synonyms: SCH
Download SVG
-2.00
0.00
2.00
4.00
6.00
8.00
10.00
12.00
14.00
16.00
OSA-80
OSA-80
MFE-296
MFE-296
M14
M14
NCI-H1703
NCI-H1703
SW1116
SW1116
ARH-77
ARH-77
HCC2935
HCC2935
UACC-62
UACC-62
EW-3
EW-3
GAK
GAK
MDA-MB-415
MDA-MB-415
WM902B
WM902B
MDA-MB-157
MDA-MB-157
BICR 56
BICR 56
RO82-W-1
RO82-W-1
BICR 22
BICR 22
MCC26
MCC26
KG-1-C
KG-1-C
DMS-79
DMS-79
HuO-3N1
HuO-3N1
REC-1
REC-1
KNS-42
KNS-42
RCC10RGB
RCC10RGB
BOKU
BOKU
Hs 936.T
Hs 936.T
U266B1
U266B1
LN-229
LN-229
SK-MEL-31
SK-MEL-31
KURAMOCHI
KURAMOCHI
SNU-410
SNU-410
H3118
H3118
KMS-11
KMS-11
HCC2998
HCC2998
ML-2
ML-2
EW-11
EW-11
KMS-34
KMS-34
NBsusSR
NBsusSR
MM1-S
MM1-S
KHM-1B
KHM-1B
BT239
BT239
LB771-HNC
LB771-HNC
VCaP
VCaP
NB(TU)1-10
NB(TU)1-10
RH-41
RH-41
ES5
ES5
EW-1
EW-1
NOS-1
NOS-1
EW-16
EW-16
KS-1
KS-1
ES1
ES1
A4-Fuk
A4-Fuk
KARPAS-620
KARPAS-620
KMS-26
KMS-26
NCI-H1355
NCI-H1355
NCI-H929
NCI-H929
Saos-2
Saos-2
201T
201T
SK-LU-1
SK-LU-1
Panc 08.13
Panc 08.13
HMV-II
HMV-II
OSA-80
MFE-296
M14
NCI-H1703
SW1116
ARH-77
HCC2935
UACC-62
EW-3
GAK
MDA-MB-415
WM902B
MDA-MB-157
BICR 56
RO82-W-1
BICR 22
MCC26
KG-1-C
DMS-79
HuO-3N1
REC-1
KNS-42
RCC10RGB
BOKU
Hs 936.T
U266B1
LN-229
SK-MEL-31
KURAMOCHI
SNU-410
H3118
KMS-11
HCC2998
ML-2
EW-11
KMS-34
NBsusSR
MM1-S
KHM-1B
BT239
LB771-HNC
VCaP
NB(TU)1-10
RH-41
ES5
EW-1
NOS-1
EW-16
KS-1
ES1
A4-Fuk
KARPAS-620
KMS-26
NCI-H1355
NCI-H929
Saos-2
201T
SK-LU-1
Panc 08.13
HMV-II
OSA-80: 17.77 (log10 µM)
Synonyms: OSA-80
MFE-296: 13.46 (log10 µM)
Synonyms: MFE-296, MFE296
M14: 9.65 (log10 µM)
Synonyms: M14
NCI-H1703: 6.80 (log10 µM)
Synonyms: NCI-H1703, NCIH1703
SW1116: 5.75 (log10 µM)
Synonyms: SW1116, SW 1116
ARH-77: 5.47 (log10 µM)
Synonyms: ARH-77
HCC2935: 5.44 (log10 µM)
Synonyms: HCC2935
UACC-62: 5.12 (log10 µM)
Synonyms: UACC-62, UACC62
EW-3: 4.61 (log10 µM)
Synonyms: EW-3
GAK: 4.29 (log10 µM)
Synonyms: GAK
MDA-MB-415: 4.24 (log10 µM)
Synonyms: MDA-MB-415, MDAMB415, mdamb415
WM902B: 4.10 (log10 µM)
Synonyms: WM902B
MDA-MB-157: 3.74 (log10 µM)
Synonyms: MDA-MB-157, MDAMB157, mdamb157
BICR 56: 3.62 (log10 µM)
Synonyms: BICR 56, BICR_56, BICR56
RO82-W-1: 3.57 (log10 µM)
Synonyms: RO82-W-1
BICR 22: 3.47 (log10 µM)
Synonyms: BICR 22, BICR_22, BICR22
MCC26: 3.41 (log10 µM)
Synonyms: MCC26
KG-1-C: 3.31 (log10 µM)
Synonyms: KG-1-C, KG1C
DMS-79: 3.07 (log10 µM)
Synonyms: DMS-79, DMS 79, DMS_79, DMS79
HuO-3N1: 3.06 (log10 µM)
Synonyms: HuO-3N1
REC-1: 2.99 (log10 µM)
Synonyms: REC-1, REC1
KNS-42: 2.80 (log10 µM)
Synonyms: KNS-42, KNS42
RCC10RGB: 2.71 (log10 µM)
Synonyms: RCC10RGB
BOKU: 2.67 (log10 µM)
Synonyms: BOKU
Hs 936.T: 2.67 (log10 µM)
Synonyms: Hs 936.T, Hs_936.T, HS936T
U266B1: 2.62 (log10 µM)
Synonyms: U266B1
LN-229: 2.47 (log10 µM)
Synonyms: LN-229, LN229
SK-MEL-31: 2.44 (log10 µM)
Synonyms: SK-MEL-31, SKMEL31
KURAMOCHI: 2.31 (log10 µM)
Synonyms: KURAMOCHI
SNU-410: 2.22 (log10 µM)
Synonyms: SNU-410, SNU410
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
H3118: -1.29 (log10 µM)
Synonyms: H3118
KMS-11: -1.32 (log10 µM)
Synonyms: KMS-11, KMS11
HCC2998: -1.33 (log10 µM)
Synonyms: HCC2998
ML-2: -1.34 (log10 µM)
Synonyms: ML-2, ML2
EW-11: -1.35 (log10 µM)
Synonyms: EW-11
KMS-34: -1.37 (log10 µM)
Synonyms: KMS-34, KMS34
NBsusSR: -1.43 (log10 µM)
Synonyms: NBsusSR
MM1-S: -1.44 (log10 µM)
Synonyms: MM1-S, MM1S, MM.1S
KHM-1B: -1.50 (log10 µM)
Synonyms: KHM-1B, KHM1B
BT239: -1.52 (log10 µM)
Synonyms: BT239
LB771-HNC: -1.57 (log10 µM)
Synonyms: LB771-HNC
VCaP: -1.59 (log10 µM)
Synonyms: VCaP, VCAP
NB(TU)1-10: -1.59 (log10 µM)
Synonyms: NB(TU)1-10
RH-41: -1.67 (log10 µM)
Synonyms: RH-41, RH41
ES5: -1.68 (log10 µM)
Synonyms: ES5
EW-1: -1.70 (log10 µM)
Synonyms: EW-1
NOS-1: -1.73 (log10 µM)
Synonyms: NOS-1
EW-16: -1.75 (log10 µM)
Synonyms: EW-16
KS-1: -1.80 (log10 µM)
Synonyms: KS-1
ES1: -1.84 (log10 µM)
Synonyms: ES1
A4-Fuk: -1.87 (log10 µM)
Synonyms: A4-Fuk, A4/Fuk, A4_Fuk, A4FUK
KARPAS-620: -1.94 (log10 µM)
Synonyms: KARPAS-620, KARPAS620
KMS-26: -1.97 (log10 µM)
Synonyms: KMS-26, KMS26
NCI-H1355: -2.03 (log10 µM)
Synonyms: NCI-H1355, NCIH1355
NCI-H929: -2.04 (log10 µM)
Synonyms: NCI-H929, NCIH929
Saos-2: -2.16 (log10 µM)
Synonyms: Saos-2, SAOS2
201T: -2.38 (log10 µM)
Synonyms: 201T
SK-LU-1: -2.51 (log10 µM)
Synonyms: SK-LU-1, SKLU1
Panc 08.13: -2.90 (log10 µM)
Synonyms: Panc 08.13, Panc_08.13, PANC-08-13, PANC0813
HMV-II: -3.12 (log10 µM)
Synonyms: HMV-II, HMVII
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
BMS-754807: AAC
AAC
Tissues
0.00
0.10
0.20
0.30
0.40
0.50
0.60
0.70
placenta
placenta
adrenal_gland
adrenal_gland
cervix
cervix
gastrointestinal_tract_(site_indeterminate)
gastrointestinal_tract_(site_indeterminate)
breast
breast
endometrium
endometrium
ovary
ovary
pleura
pleura
urinary_tract
urinary_tract
skin
skin
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
central_nervous_system
central_nervous_system
kidney
kidney
thyroid
thyroid
upper_aerodigestive_tract
upper_aerodigestive_tract
oral_cavity
oral_cavity
stomach
stomach
head_and_neck
head_and_neck
liver
liver
misc
misc
lung
lung
oesophagus
oesophagus
soft_tissue
soft_tissue
pancreas
pancreas
testis
testis
biliary_tract
biliary_tract
unknown
unknown
prostate
prostate
large_intestine
large_intestine
vulva
vulva
bone
bone
other
other
autonomic_ganglia
autonomic_ganglia
small_intestine
small_intestine
salivary_gland
salivary_gland
neuroblastoma
neuroblastoma
-3.00
-2.00
-1.00
0.00
1.00
2.00
3.00
neuroblastoma
neuroblastoma
small_intestine
small_intestine
autonomic_ganglia
autonomic_ganglia
bone
bone
vulva
vulva
misc
misc
oral_cavity
oral_cavity
large_intestine
large_intestine
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
unknown
unknown
soft_tissue
soft_tissue
testis
testis
lung
lung
breast
breast
pancreas
pancreas
thyroid
thyroid
oesophagus
oesophagus
stomach
stomach
skin
skin
salivary_gland
salivary_gland
urinary_tract
urinary_tract
adrenal_gland
adrenal_gland
prostate
prostate
head_and_neck
head_and_neck
upper_aerodigestive_tract
upper_aerodigestive_tract
ovary
ovary
biliary_tract
biliary_tract
central_nervous_system
central_nervous_system
pleura
pleura
kidney
kidney
liver
liver
endometrium
endometrium
other
other
gastrointestinal_tract_(site_indeterminate)
gastrointestinal_tract_(site_indeterminate)
cervix
cervix
placenta
placenta
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to BMS-754807
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
TRRAP
CTRPv2
pan-cancer
AAC
0.15
2e-05
mRNA
HACD1
CTRPv2
pan-cancer
AAC
-0.15
2e-05
mRNA
CTBP1
GDSC1000
pan-cancer
AAC
0.14
2e-05
mRNA
GAS2
CTRPv2
pan-cancer
AAC
0.14
2e-05
mRNA
IQSEC3
CTRPv2
pan-cancer
AAC
0.14
2e-05
mRNA
CD86
GDSC1000
pan-cancer
AAC
-0.17
2e-05
mRNA
EPS15
GDSC1000
pan-cancer
AAC
-0.15
2e-05
mRNA
SERPINB9
CTRPv2
pan-cancer
AAC
-0.15
2e-05
mRNA
NFX1
CTRPv2
pan-cancer
AAC
0.16
2e-05
mRNA
RPL26L1
CTRPv2
pan-cancer
AAC
-0.16
2e-05
← Previous
1
2
…
32
33
34
…
199
200
Next →
Download CSV