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etoposide

Synonyms

SourcesNames Used
GDSC1000, GRAYEtoposide
CTRPv2etoposide
PharmacoGx etoposide

External IDs

DatabaseIdentifier
Smiles: COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)C(OC4OC5COC(C)OC5C(O)C4O)c6cc7OCOc7cc26
Inchikey: VJJPUSNTGOMMGY-MRVIYFEKSA-N
Pubchem: 36462

Annotated Targets

TOP2A, TOP2B

FDA Approval Status

Approved
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Top molecular features associated with response to etoposide


Feature TypeStandardized
Nominal ANOVA
mRNA RCOR3 CTRPv2 pan-cancer AAC 0.15 1e-06
mRNA RNGTT CTRPv2 pan-cancer AAC 0.15 1e-06
mRNA STRADA CTRPv2 pan-cancer AAC 0.16 1e-06
mRNA TRIM22 CTRPv2 pan-cancer AAC 0.15 1e-06
mRNA FAH CTRPv2 pan-cancer AAC -0.15 1e-06
mRNA SEPT6 CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA AHNAK CTRPv2 pan-cancer AAC -0.16 2e-06
mRNA ZNF638 CTRPv2 pan-cancer AAC 0.14 2e-06
mRNA SALL2 CTRPv2 pan-cancer AAC 0.15 2e-06
mRNA PHF11 CTRPv2 pan-cancer AAC 0.16 2e-06
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