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etoposide

Synonyms

SourcesNames Used
GDSC1000, GRAYEtoposide
CTRPv2etoposide
PharmacoGx etoposide

External IDs

DatabaseIdentifier
Smiles: COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)C(OC4OC5COC(C)OC5C(O)C4O)c6cc7OCOc7cc26
Inchikey: VJJPUSNTGOMMGY-MRVIYFEKSA-N
Pubchem: 36462

Annotated Targets

TOP2A, TOP2B

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to etoposide


Feature TypeStandardized
Nominal ANOVA
mRNA CCDC6 GDSC1000 pan-cancer AAC -0.14 0.0004
mRNA WASF1 GDSC1000 pan-cancer AAC 0.14 0.0004
mRNA GUCA2A GDSC1000 pan-cancer AAC -0.13 0.0004
mRNA DDX21 GDSC1000 pan-cancer AAC 0.13 0.0004
mRNA SLC5A2 CTRPv2 pan-cancer AAC -0.1 0.0004
mRNA SHANK1 CTRPv2 pan-cancer AAC 0.11 0.0004
mRNA LIG4 GDSC1000 pan-cancer AAC 0.13 0.0004
mRNA ADAMTSL5 CTRPv2 pan-cancer AAC -0.11 0.0004
mRNA SGSM3 CTRPv2 pan-cancer AAC 0.11 0.0004
mRNA BAD CTRPv2 pan-cancer AAC -0.12 0.0004
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