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etoposide

Synonyms

SourcesNames Used
GDSC1000, GRAYEtoposide
CTRPv2etoposide
PharmacoGx etoposide

External IDs

DatabaseIdentifier
Smiles: COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)C(OC4OC5COC(C)OC5C(O)C4O)c6cc7OCOc7cc26
Inchikey: VJJPUSNTGOMMGY-MRVIYFEKSA-N
Pubchem: 36462

Annotated Targets

TOP2A, TOP2B

FDA Approval Status

Approved
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Top molecular features associated with response to etoposide


Feature TypeStandardized
Nominal ANOVA
mRNA HNRNPDL GDSC1000 pan-cancer AAC 0.14 0.0003
mRNA TMEM184B GDSC1000 pan-cancer AAC -0.15 0.0003
mRNA DFNB59 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA RP3-369A17.6 CTRPv2 pan-cancer AAC 0.12 0.0003
mRNA PARVA CTRPv2 pan-cancer AAC -0.13 0.0003
mRNA CA11 CTRPv2 pan-cancer AAC 0.11 0.0003
mRNA PIGK CTRPv2 pan-cancer AAC -0.12 0.0003
mRNA HTATIP2 GDSC1000 pan-cancer AAC -0.15 0.0003
mRNA USF1 GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA SPIN1 GDSC1000 pan-cancer AAC 0.14 0.0003
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