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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA MYOF GDSC1000 pan-cancer AAC 0.33 2e-13
mRNA NOL4 GDSC1000 pan-cancer AAC -0.25 2e-13
mRNA ARPC1B GDSC1000 pan-cancer AAC 0.25 2e-13
mRNA RUNX1T1 gCSI pan-cancer AAC -0.39 3e-13
mRNA FAH GDSC1000 pan-cancer AAC 0.25 3e-13
mRNA JAKMIP2 GDSC1000 pan-cancer AAC -0.27 3e-13
mRNA ITGB5 GDSC1000 pan-cancer AAC 0.3 3e-13
mRNA CHP1 GDSC1000 pan-cancer AAC 0.25 4e-13
mRNA FUCA2 GDSC1000 pan-cancer AAC 0.27 4e-13
mRNA DUSP6 GDSC1000 pan-cancer AAC 0.24 4e-13
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