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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA DOCK5 GDSC1000 pan-cancer AAC 0.24 4e-13
mRNA HSD17B6 gCSI pan-cancer AAC -0.38 5e-13
mRNA FCER1G GDSC1000 pan-cancer AAC 0.24 5e-13
mRNA MYL12A GDSC1000 pan-cancer AAC 0.25 6e-13
mRNA IGF2BP2 GDSC1000 pan-cancer AAC 0.27 6e-13
mRNA INSM1 GDSC1000 pan-cancer AAC -0.26 6e-13
mRNA LYZ GDSC1000 pan-cancer AAC 0.24 7e-13
mRNA GKAP1 GDSC1000 pan-cancer AAC -0.25 7e-13
mRNA LPCAT2 GDSC1000 pan-cancer AAC 0.24 8e-13
mRNA NQO1 GDSC1000 pan-cancer AAC 0.3 8e-13
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