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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA CCP110 GDSC1000 pan-cancer AAC -0.25 8e-13
mRNA PURG GDSC1000 pan-cancer AAC -0.26 8e-13
mRNA YPEL1 GDSC1000 pan-cancer AAC -0.25 9e-13
mRNA DHX32 GDSC1000 pan-cancer AAC 0.28 9e-13
mRNA AUTS2 GDSC1000 pan-cancer AAC -0.25 1e-12
mRNA SLC22A15 GDSC1000 pan-cancer AAC 0.22 1e-12
mRNA TIFA GDSC1000 pan-cancer AAC -0.32 1e-12
mRNA NPAS2 CCLE pan-cancer AAC 0.32 1e-12
mRNA KIF5C GDSC1000 pan-cancer AAC -0.25 1e-12
mRNA SAFB GDSC1000 pan-cancer AAC -0.29 2e-12
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