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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA RNASE2 GDSC1000 pan-cancer AAC 0.22 1e-11
mRNA RALB gCSI pan-cancer AAC 0.36 1e-11
mRNA CLIC1 gCSI pan-cancer AAC 0.35 1e-11
mRNA TCF4 gCSI pan-cancer AAC -0.43 1e-11
mRNA GCSAM GDSC1000 pan-cancer AAC -0.28 1e-11
mRNA PTPN12 GDSC1000 pan-cancer AAC 0.27 1e-11
mRNA TSPAN4 GDSC1000 pan-cancer AAC 0.27 1e-11
mRNA TPP1 GDSC1000 pan-cancer AAC 0.23 2e-11
mRNA MFSD1 GDSC1000 pan-cancer AAC 0.21 2e-11
mRNA AGTRAP GDSC1000 pan-cancer AAC 0.24 2e-11
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