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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA TSPYL4 GDSC1000 pan-cancer AAC -0.24 2e-12
mRNA VASP GDSC1000 pan-cancer AAC 0.24 2e-12
mRNA TSR2 GDSC1000 pan-cancer AAC -0.22 2e-12
mRNA TOR4A GDSC1000 pan-cancer AAC 0.25 2e-12
mRNA ZNF775 GDSC1000 pan-cancer AAC -0.25 2e-12
mRNA RALB GDSC1000 pan-cancer AAC 0.24 2e-12
mRNA CYFIP2 GDSC1000 pan-cancer AAC -0.29 2e-12
mRNA ANXA4 GDSC1000 pan-cancer AAC 0.28 2e-12
mRNA MGAT4B GDSC1000 pan-cancer AAC 0.27 2e-12
mRNA TOR1AIP1 GDSC1000 pan-cancer AAC 0.22 2e-12
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