1. Home/
  2. Compounds/
  3. PD-0325901

PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA LTBR GDSC1000 pan-cancer AAC 0.41 1e-22
mRNA SPRY2 CCLE pan-cancer AAC 0.43 9e-21
mRNA TIMP1 GDSC1000 pan-cancer AAC 0.32 3e-20
mRNA S100A11 GDSC1000 pan-cancer AAC 0.34 2e-19
mRNA CD68 GDSC1000 pan-cancer AAC 0.31 6e-19
mRNA LMNA GDSC1000 pan-cancer AAC 0.37 1e-18
mRNA SPRY2 GDSC1000 pan-cancer AAC 0.31 1e-18
mRNA CD63 GDSC1000 pan-cancer AAC 0.36 2e-18
mRNA ACTN1 GDSC1000 pan-cancer AAC 0.36 2e-18
mRNA CTSB GDSC1000 pan-cancer AAC 0.33 3e-18
Download CSV