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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA EBF1 CCLE pan-cancer AAC -0.21 6e-06
mRNA MICA gCSI pan-cancer AAC 0.26 6e-06
mRNA SCMH1 gCSI pan-cancer AAC -0.23 6e-06
mRNA RASAL2 gCSI pan-cancer AAC 0.31 6e-06
mRNA ENPP4 GDSC1000 pan-cancer AAC -0.16 6e-06
mRNA PYGB CCLE pan-cancer AAC 0.22 6e-06
mRNA CAMK2B gCSI pan-cancer AAC -0.22 6e-06
mRNA TUBA1C GDSC1000 pan-cancer AAC 0.18 6e-06
mRNA RPS6KA4 GDSC1000 pan-cancer AAC 0.16 6e-06
mRNA HMGB2 GDSC1000 pan-cancer AAC -0.16 6e-06
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