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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA BACH2 CCLE pan-cancer AAC -0.32 4e-12
mRNA PRNP GDSC1000 pan-cancer AAC 0.25 4e-12
mRNA ELK3 GDSC1000 pan-cancer AAC 0.23 5e-12
mRNA SPRY4 CCLE pan-cancer AAC 0.33 5e-12
mRNA SQSTM1 GDSC1000 pan-cancer AAC 0.25 5e-12
mRNA MLKL GDSC1000 pan-cancer AAC 0.24 6e-12
mRNA TYROBP GDSC1000 pan-cancer AAC 0.23 6e-12
mRNA GADD45G GDSC1000 pan-cancer AAC -0.23 6e-12
mRNA CARMIL2 GDSC1000 pan-cancer AAC -0.28 6e-12
mRNA HSD17B6 CCLE pan-cancer AAC -0.31 7e-12
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