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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA KDELR3 GDSC1000 pan-cancer AAC 0.31 2e-12
mRNA HEBP1 GDSC1000 pan-cancer AAC 0.28 3e-12
mRNA EPB41 GDSC1000 pan-cancer AAC -0.26 3e-12
mRNA ATP6V1G2 gCSI pan-cancer AAC -0.42 3e-12
mRNA ARAP3 GDSC1000 pan-cancer AAC 0.24 3e-12
mRNA LATS2 GDSC1000 pan-cancer AAC 0.25 3e-12
mRNA FBXO21 GDSC1000 pan-cancer AAC -0.25 4e-12
mRNA MYO1F GDSC1000 pan-cancer AAC 0.25 4e-12
mRNA POU2AF1 GDSC1000 pan-cancer AAC -0.31 4e-12
mRNA FCER1G CCLE pan-cancer AAC 0.3 4e-12
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