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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA ANXA1 CCLE pan-cancer AAC 0.22 6e-06
mRNA UEVLD GDSC1000 pan-cancer AAC 0.17 6e-06
mRNA ORAI1 GDSC1000 pan-cancer AAC 0.15 6e-06
mRNA FPGT gCSI pan-cancer AAC 0.23 6e-06
mRNA KIF5A gCSI pan-cancer AAC -0.25 6e-06
mRNA IKZF3 GDSC1000 pan-cancer AAC -0.18 6e-06
mRNA LAPTM4B CCLE pan-cancer AAC 0.26 6e-06
mRNA SLMAP GDSC1000 pan-cancer AAC 0.16 6e-06
mRNA PYGL CCLE pan-cancer AAC 0.2 6e-06
mRNA LAMTOR1 GDSC1000 pan-cancer AAC 0.15 6e-06
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