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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA S100A10 gCSI pan-cancer AAC 0.27 5e-06
mRNA SMDT1 GDSC1000 pan-cancer AAC -0.17 5e-06
mRNA LRRC8C gCSI pan-cancer AAC 0.24 5e-06
mRNA LPCAT2 gCSI pan-cancer AAC 0.25 5e-06
mRNA CTSG gCSI pan-cancer AAC 0.23 5e-06
mRNA PHF21B GDSC1000 pan-cancer AAC -0.16 5e-06
mRNA EPM2A gCSI pan-cancer AAC -0.26 5e-06
mRNA RASSF6 GDSC1000 pan-cancer AAC -0.15 5e-06
mRNA ZPBP2 CCLE pan-cancer AAC -0.2 6e-06
mRNA IL21R GDSC1000 pan-cancer AAC -0.19 6e-06
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