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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF91 GDSC1000 pan-cancer AAC -0.16 5e-06
mRNA ARRDC2 GDSC1000 pan-cancer AAC 0.16 5e-06
mRNA ANTXR2 gCSI pan-cancer AAC 0.24 5e-06
mRNA ROPN1L GDSC1000 pan-cancer AAC 0.14 5e-06
mRNA UBE2QL1 GDSC1000 pan-cancer AAC -0.15 5e-06
mRNA C16orf71 gCSI pan-cancer AAC -0.23 5e-06
mRNA SLC25A53 gCSI pan-cancer AAC -0.24 5e-06
mRNA PLAU GDSC1000 pan-cancer AAC 0.17 5e-06
mRNA CDK5R2 gCSI pan-cancer AAC -0.24 5e-06
mRNA C4orf46 GDSC1000 pan-cancer AAC -0.18 5e-06
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