1. Home/
  2. Compounds/
  3. NVP-BEZ235

NVP-BEZ235

Synonyms

SourcesNames Used
GDSC1000, GRAYBEZ235
CTRPv2NVP-BEZ235
PharmacoGx NVP-BEZ235

External IDs

DatabaseIdentifier
Smiles: CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3N(C2=O)C)C5=CC6=CC=CC=C6N=C5
Inchikey: JOGKUKXHTYWRGZ-UHFFFAOYSA-N
Pubchem: 11977753

Annotated Targets

ATR, MTOR, PIK3CA, PIK3CD, PIK3CG, PIK3CB

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to NVP-BEZ235


Feature TypeStandardized
Nominal ANOVA
mRNA ST18 GDSC1000 pan-cancer AAC -0.2 4e-08
mRNA STK17A GDSC1000 pan-cancer AAC 0.21 4e-08
mRNA OVOL2 GDSC1000 pan-cancer AAC -0.24 5e-08
mRNA COQ8A GDSC1000 pan-cancer AAC -0.2 7e-08
mRNA PTRF GDSC1000 pan-cancer AAC 0.23 1e-07
mRNA SNAP23 GDSC1000 pan-cancer AAC 0.21 1e-07
mRNA KIF1A GDSC1000 pan-cancer AAC -0.21 1e-07
mRNA LGALS1 GDSC1000 pan-cancer AAC 0.2 1e-07
mRNA ADAM9 GDSC1000 pan-cancer AAC 0.25 1e-07
mRNA ACO1 GDSC1000 pan-cancer AAC 0.2 1e-07
Download CSV