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NVP-BEZ235

Synonyms

SourcesNames Used
GDSC1000, GRAYBEZ235
CTRPv2NVP-BEZ235
PharmacoGx NVP-BEZ235

External IDs

DatabaseIdentifier
Smiles: CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3N(C2=O)C)C5=CC6=CC=CC=C6N=C5
Inchikey: JOGKUKXHTYWRGZ-UHFFFAOYSA-N
Pubchem: 11977753

Annotated Targets

ATR, MTOR, PIK3CA, PIK3CD, PIK3CG, PIK3CB

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to NVP-BEZ235


Feature TypeStandardized
Nominal ANOVA
mRNA FLNB GDSC1000 pan-cancer AAC 0.13 0.003
mRNA COX4I2 CTRPv2 pan-cancer AAC -0.12 0.003
mRNA KLK11 GDSC1000 pan-cancer AAC -0.1 0.003
mRNA LUZP1 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA RELT GDSC1000 pan-cancer AAC -0.11 0.003
mRNA C11orf70 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA TRIM9 GDSC1000 pan-cancer AAC -0.11 0.003
mRNA SPCS3 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA PPP1R36 GDSC1000 pan-cancer AAC -0.11 0.003
mRNA ADGRE5 GDSC1000 pan-cancer AAC 0.11 0.003
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