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BIBW2992

Synonyms

SourcesNames Used
GDSC1000, FIMMAfatinib
GRAYBIBW2992
CTRPv2afatinib
PharmacoGx BIBW2992

External IDs

DatabaseIdentifier
Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Inchikey: ULXXDDBFHOBEHA-CWDCEQMOSA-N
Pubchem: 10184653

FDA Approval Status

Approved
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Top molecular features associated with response to BIBW2992


Feature TypeStandardized
Nominal ANOVA
mRNA ZXDC CTRPv2 pan-cancer AAC 0.11 0.005
mRNA ZSCAN26 CTRPv2 pan-cancer AAC -0.14 0.0002
mRNA ZPLD1 CTRPv2 pan-cancer AAC 0.088 0.01
mRNA ZNRF2 CTRPv2 pan-cancer AAC 0.13 0.0005
mRNA ZNF837 CTRPv2 pan-cancer AAC 0.098 0.008
mRNA ZNF81 CTRPv2 pan-cancer AAC -0.12 0.002
mRNA ZNF778 CTRPv2 pan-cancer AAC -0.1 0.01
mRNA ZNF775 CTRPv2 pan-cancer AAC -0.1 0.009
mRNA ZNF750 CTRPv2 pan-cancer AAC 0.12 0.003
mRNA ZNF74 FIMM pan-cancer AAC 0.4 0.01
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