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BIBW2992

Synonyms

SourcesNames Used
GDSC1000, FIMMAfatinib
GRAYBIBW2992
CTRPv2afatinib
PharmacoGx BIBW2992

External IDs

DatabaseIdentifier
Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Inchikey: ULXXDDBFHOBEHA-CWDCEQMOSA-N
Pubchem: 10184653

FDA Approval Status

Approved
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Top molecular features associated with response to BIBW2992


Feature TypeStandardized
Nominal ANOVA
mRNA NRIP1 FIMM pan-cancer AAC 0.38 0.02
mRNA SPA17 FIMM pan-cancer AAC -0.39 0.02
mRNA MLX FIMM pan-cancer AAC -0.42 0.02
mRNA PRR14L FIMM pan-cancer AAC 0.37 0.02
mRNA B3GALT1 FIMM pan-cancer AAC 0.36 0.02
mRNA ZNF254 FIMM pan-cancer AAC 0.35 0.02
mRNA SPRY1 FIMM pan-cancer AAC 0.37 0.02
mRNA SPTBN5 FIMM pan-cancer AAC 0.38 0.02
mRNA PLPP3 FIMM pan-cancer AAC 0.48 0.02
mRNA TMEM243 FIMM pan-cancer AAC -0.36 0.01
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