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BIBW2992

Synonyms

SourcesNames Used
GDSC1000, FIMMAfatinib
GRAYBIBW2992
CTRPv2afatinib
PharmacoGx BIBW2992

External IDs

DatabaseIdentifier
Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Inchikey: ULXXDDBFHOBEHA-CWDCEQMOSA-N
Pubchem: 10184653

FDA Approval Status

Approved
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Top molecular features associated with response to BIBW2992


Feature TypeStandardized
Nominal ANOVA
mRNA SPCS1 FIMM pan-cancer AAC -0.5 0.001
mRNA ACSBG2 FIMM pan-cancer AAC -0.49 0.001
mRNA B4GALT4 FIMM pan-cancer AAC -0.48 0.008
mRNA IFT57 FIMM pan-cancer AAC -0.48 0.001
mRNA NNT FIMM pan-cancer AAC -0.47 0.008
mRNA GPR50 FIMM pan-cancer AAC -0.45 0.002
mRNA GLRX FIMM pan-cancer AAC -0.44 0.008
mRNA TCFL5 FIMM pan-cancer AAC -0.44 0.004
mRNA GLI2 FIMM pan-cancer AAC -0.44 0.002
mRNA HLA-G FIMM pan-cancer AAC -0.44 0.006
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