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BIBW2992

Synonyms

SourcesNames Used
GDSC1000, FIMMAfatinib
GRAYBIBW2992
CTRPv2afatinib
PharmacoGx BIBW2992

External IDs

DatabaseIdentifier
Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Inchikey: ULXXDDBFHOBEHA-CWDCEQMOSA-N
Pubchem: 10184653

FDA Approval Status

Approved
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Top molecular features associated with response to BIBW2992


Feature TypeStandardized
Nominal ANOVA
mRNA GJB5 CTRPv2 pan-cancer AAC 0.23 5e-07
mRNA NMT2 CTRPv2 pan-cancer AAC -0.19 6e-07
mRNA KDF1 CTRPv2 pan-cancer AAC 0.23 6e-07
mRNA ELMO3 CTRPv2 pan-cancer AAC 0.22 7e-07
mRNA TCAP CTRPv2 pan-cancer AAC 0.18 8e-07
mRNA TNK1 CTRPv2 pan-cancer AAC 0.24 9e-07
mRNA EPCAM CTRPv2 pan-cancer AAC 0.22 1e-06
mRNA AP1M2 CTRPv2 pan-cancer AAC 0.22 1e-06
mRNA TRDMT1 CTRPv2 pan-cancer AAC -0.18 1e-06
mRNA CLDN7 CTRPv2 pan-cancer AAC 0.21 1e-06
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