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BIBW2992

Synonyms

SourcesNames Used
GDSC1000, FIMMAfatinib
GRAYBIBW2992
CTRPv2afatinib
PharmacoGx BIBW2992

External IDs

DatabaseIdentifier
Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Inchikey: ULXXDDBFHOBEHA-CWDCEQMOSA-N
Pubchem: 10184653

FDA Approval Status

Approved
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Top molecular features associated with response to BIBW2992


Feature TypeStandardized
Nominal ANOVA
mRNA STX2 CTRPv2 pan-cancer AAC -0.25 2e-09
mRNA OVOL1 CTRPv2 pan-cancer AAC 0.26 2e-09
mRNA FAM83H-AS1 CTRPv2 pan-cancer AAC 0.25 3e-09
mRNA MIEN1 CTRPv2 pan-cancer AAC 0.22 3e-09
mRNA PGAP3 CTRPv2 pan-cancer AAC 0.22 4e-09
mRNA EGFR CTRPv2 pan-cancer AAC 0.23 4e-09
mRNA GRHL2 CTRPv2 pan-cancer AAC 0.26 5e-09
mRNA CDC42BPG CTRPv2 pan-cancer AAC 0.26 6e-09
mRNA IRF6 CTRPv2 pan-cancer AAC 0.27 6e-09
mRNA EPN3 CTRPv2 pan-cancer AAC 0.24 7e-09
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