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BIBW2992

Synonyms

SourcesNames Used
GDSC1000, FIMMAfatinib
GRAYBIBW2992
CTRPv2afatinib
PharmacoGx BIBW2992

External IDs

DatabaseIdentifier
Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Inchikey: ULXXDDBFHOBEHA-CWDCEQMOSA-N
Pubchem: 10184653

FDA Approval Status

Approved
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Top molecular features associated with response to BIBW2992


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF254 FIMM pan-cancer AAC 0.35 0.02
mRNA ZNF35 CTRPv2 pan-cancer AAC -0.093 0.01
mRNA ZNF367 CTRPv2 pan-cancer AAC -0.11 0.003
mRNA ZNF444 CTRPv2 pan-cancer AAC 0.1 0.005
mRNA ZNF524 CTRPv2 pan-cancer AAC 0.096 0.01
mRNA ZNF525 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA ZNF555 CTRPv2 pan-cancer AAC -0.12 0.002
mRNA ZNF600 CTRPv2 pan-cancer AAC 0.1 0.006
mRNA ZNF646 FIMM pan-cancer AAC 0.45 0.004
mRNA ZNF697 CTRPv2 pan-cancer AAC -0.15 0.0005
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