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BIBW2992

Synonyms

SourcesNames Used
GDSC1000, FIMMAfatinib
GRAYBIBW2992
CTRPv2afatinib
PharmacoGx BIBW2992

External IDs

DatabaseIdentifier
Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Inchikey: ULXXDDBFHOBEHA-CWDCEQMOSA-N
Pubchem: 10184653

FDA Approval Status

Approved
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Top molecular features associated with response to BIBW2992


Feature TypeStandardized
Nominal ANOVA
mRNA SMIM22 CTRPv2 pan-cancer AAC 0.19 9e-06
mRNA RP1-4G17.5 CTRPv2 pan-cancer AAC 0.19 1e-05
mRNA BAIAP2 CTRPv2 pan-cancer AAC 0.18 1e-05
mRNA CDH3 CTRPv2 pan-cancer AAC 0.2 1e-05
mRNA TMC4 CTRPv2 pan-cancer AAC 0.18 1e-05
mRNA CRB3 CTRPv2 pan-cancer AAC 0.19 1e-05
mRNA ARHGAP8 CTRPv2 pan-cancer AAC 0.19 1e-05
mRNA TFE3 CTRPv2 pan-cancer AAC -0.18 1e-05
mRNA B3GNT3 CTRPv2 pan-cancer AAC 0.19 1e-05
mRNA ITGB6 CTRPv2 pan-cancer AAC 0.17 1e-05
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