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BIBW2992

Synonyms

SourcesNames Used
GDSC1000, FIMMAfatinib
GRAYBIBW2992
CTRPv2afatinib
PharmacoGx BIBW2992

External IDs

DatabaseIdentifier
Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
Inchikey: ULXXDDBFHOBEHA-CWDCEQMOSA-N
Pubchem: 10184653

FDA Approval Status

Approved
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Top molecular features associated with response to BIBW2992


Feature TypeStandardized
Nominal ANOVA
mRNA SEC61G CTRPv2 pan-cancer AAC 0.19 6e-08
mRNA MLLT6 CTRPv2 pan-cancer AAC 0.2 8e-08
mRNA LSR CTRPv2 pan-cancer AAC 0.23 1e-07
mRNA CTSV CTRPv2 pan-cancer AAC 0.21 1e-07
mRNA MAL2 CTRPv2 pan-cancer AAC 0.22 1e-07
mRNA TRPM4 CTRPv2 pan-cancer AAC 0.21 2e-07
mRNA ESRP2 CTRPv2 pan-cancer AAC 0.24 2e-07
mRNA DDR1 CTRPv2 pan-cancer AAC 0.23 2e-07
mRNA PSD4 CTRPv2 pan-cancer AAC 0.23 2e-07
mRNA LANCL2 CTRPv2 pan-cancer AAC 0.18 2e-07
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