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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA MARCKSL1 CTRPv2 pan-cancer AAC 0.21 4e-09
mRNA SCML2 CTRPv2 pan-cancer AAC 0.21 4e-09
mRNA MTMR4 CTRPv2 pan-cancer AAC 0.22 5e-09
mRNA H3F3A CTRPv2 pan-cancer AAC 0.22 5e-09
mRNA BEND5 CTRPv2 pan-cancer AAC 0.21 5e-09
mRNA KLHL23 CTRPv2 pan-cancer AAC 0.22 5e-09
mRNA TNMD CTRPv2 pan-cancer AAC 0.2 5e-09
mRNA RBM10 CTRPv2 pan-cancer AAC 0.22 5e-09
mRNA ZNF678 CTRPv2 pan-cancer AAC 0.21 6e-09
mRNA DNMT3A CTRPv2 pan-cancer AAC 0.22 6e-09
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