PharmacoDB

Sources

Names Used

Temsirolimus

temsirolimus

PharmacoGx

temsirolimus

Database	Identifier
Smiles:	CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
Inchikey:	CBPNZQVSJQDFBE-FUXHJELOSA-N
Pubchem:	6918289

Database

Identifier

Smiles:

CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC

Inchikey:

CBPNZQVSJQDFBE-FUXHJELOSA-N

Pubchem:

Top molecular features associated with response to temsirolimus

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ARL2BP	GDSC1000	pan-cancer	AAC	0.12	0.0004
mRNA	FAM214A	CTRPv2	pan-cancer	AAC	0.18	0.0004
mRNA	TFF3	GDSC1000	pan-cancer	AAC	-0.13	0.0004
mRNA	HDAC5	GDSC1000	pan-cancer	AAC	-0.13	0.0004
mRNA	MS4A10	GDSC1000	pan-cancer	AAC	-0.12	0.0005
mRNA	UEVLD	GDSC1000	pan-cancer	AAC	0.14	0.0005
mRNA	ANXA5	GDSC1000	pan-cancer	AAC	0.13	0.0005
mRNA	ST6GALNAC1	GDSC1000	pan-cancer	AAC	-0.12	0.0005
mRNA	FAM120A	GDSC1000	pan-cancer	AAC	0.13	0.0005
mRNA	ENO2	GDSC1000	pan-cancer	AAC	-0.13	0.0005